With 300 new illustrations, diagrams, and radiology studies including PET scans, Principles of Neural Science, 6th Edition is the definitive guide for neuroscientists, neurologists, psychiatrists, students, and residents. Highly detailed chapters on stroke, Parkinson’s, and MS build your expertise on these critical topics. Radiological studies the authors have chosen explain what’s most important to know and understand for each type of stroke, progressive MS, or non-progressive MS.

Features

• 2,200 images, including 300 new color illustrations, diagrams, and radiology studies (including PET scans)
• NEW: This edition now features only two contributors per chapter and are mostly U.S.-based
• NEW: Number of chapters streamlined down from 67 to 60
• NEW: Chapter on Navigation and Spatial Memory
• NEW: New images in every chapter!

Table of Contents

Part I Overall Perspective

1 The Brain and Behavior

2 Genes and Behavior

3 Nerve Cells, Neural Circuitry, and Behavior

4 The Neuroanatomical Bases by Which Neural

Circuits Mediate Behavior

5 The Computational Bases of Neural Circuits

That Mediate Behavior

6 Imaging and Behavior

Part II Cell and Molecular Biology of Cells of the Nervous System

7 The Cells of the Nervous System

8 Ion Channels 165

9 Membrane Potential and the Passive Electrical

Properties of the Neuron

10 Propagated Signaling: The Action Potential

Part III Synaptic Transmission

11 Overview of Synaptic Transmission

12 Directly Gated Transmission: The Nerve-Muscle Synapse

13 Synaptic Integration in the Central Nervous System

14 Modulation of Synaptic Transmission and Neuronal Excitability: Second Messengers

15 Transmitter Release

16 Neurotransmitters

Part IV Perception

17 Sensory Coding

18 Receptors of the Somatosensory System

19 Touch

20 Pain

21 The Constructive Nature of Visual Processing

22 Low-Level Visual Processing: The Retina

23 Intermediate-Level Visual Processing and Visual Primitives

24 High-Level Visual Processing: From Vision to Cognition

25 Visual Processing for Attention and Action

26 Auditory Processing by the Cochlea

27 The Vestibular System

28 Auditory Processing by the Central Nervous System

29 Smell and Taste: The Chemical Senses

Part V Movement

30 Principles of Sensorimotor Control

31 The Motor Unit and Muscle Action

32 Sensory-Motor Integration in the Spinal Cord

33 Locomotion

34 Voluntary Movement: Motor Cortices

35 The Control of Gaze

36 Posture

37 The Cerebellum

38 The Basal Ganglia

39 Brain–Machine Interfaces

Part IV Perception

17 Sensory Coding

18 Receptors of the Somatosensory System

19 Touch

20 Pain

21 The Constructive Nature of Visual Processing

22 Low-Level Visual Processing: The Retina

23 Intermediate-Level Visual Processing and Visual Primitives

24 High-Level Visual Processing: From Vision to Cognition

25 Visual Processing for Attention and Action

26 Auditory Processing by the Cochlea

27 The Vestibular System

28 Auditory Processing by the Central Nervous System

29 Smell and Taste: The Chemical Senses

Part VII Development and the Emergence of Behavior

45 Patterning the Nervous System

46 Differentiation and Survival of Nerve Cells

47 The Growth and Guidance of Axons

48 Formation and Elimination of Synapses

49 Experience and the Refinement of Synaptic Connections

50 Repairing the Damaged Brain

51 Sexual Differentiation of the Nervous System

Part VIII Learning, Memory, Language and Cognition

52 Learning and Memory

53 Cellular Mechanisms of Implicit Memory Storage

and the Biological Basis of Individuality

54 The Hippocampus and the Neural Basis of Explicit Memory Storage

55 Language

56 Decision-Making and Consciousness

Part IX Diseases of the Nervous System

57 Diseases of the Peripheral Nerve and Motor Unit

58 Seizures and Epilepsy

59 Disorders of Conscious and Unconscious Mental Processes

60 Disorders of Thought and Volition in Schizophrenia

61 Disorders of Mood and Anxiety

62 Disorders Affecting Social Cognition: Autism Spectrum Disorder

63 Genetic Mechanisms in Neurodegenerative Diseases of the Nervous System

64 The Aging Brain

About the Author

Eric R. Kandel is Kavli Professor and University Professor at Columbia University and senior investigator at the Howard Hughes Medical Institute. He received the Nobel Prize in Physiology or Medicine in 2000. He lives in New York City.